MKLP1 Antibody (YA9967)
(Synonyms: CDAN3A; CDAN3; CDA3; CHO1)MKLP1 Antibody (YA9967) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to MKLP1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:100-1000 |
Product Details
MKLP1 Antibody (YA9967) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to MKLP1.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 110-120kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 110kDa
Synthetic peptide corresponding to Human MKLP1.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MKLP1 is a Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro
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Subcellular Localization
Nucleus; Cytoplasm, cytoskeleton, spindle; Midbody, Midbody ring; Midbody
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Expression
Tissue_Specificity: Widely expressed. -
Isoforms & Post-Translational Modification
MKLP1 has 3 isoforms, Q02241-1: amino acid length is 960, molecular weight is 110059 Da (predicted); Q02241-2: amino acid length is 856, molecular weight is 98105 Da (predicted); Q02241-3: amino acid length is 673, molecular weight is 77699 Da (predicted).Ubiquitinated. Deubiquitinated by USP8/UBPY
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Subunit
Heterotetramer of two molecules each of RACGAP1 and KIF23.
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SwissProt ID
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Synonyms
CDAN3A; CDAN3; CDA3; CHO1
Documentation
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