MRPS27 Antibody (YA8293)
(Synonyms: MRP-S27; S27mt)MRPS27 Antibody (YA8293) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MRPS27.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
MRPS27 Antibody (YA8293) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MRPS27.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 47.4 kDa
Human recombinant protein fragment corresponding to amino acids 151-414 of human MRPS27 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MRPS27 is a RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth[1][2].
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Subcellular Localization
Cytoplasm,Mitochondrion
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Expression
Tissue_Specificity: Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level) (PubMed:28714366). Ubiquitous (PubMed:22841715) -
Isoforms & Post-Translational Modification
Q92552 has two isomers: Q92552-1: 47611 Da (predicted); Q92552-2: 49150 Da (predicted).
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Subunit
Component of the mitochondrial small ribosomal subunit (mt-SSU) (PubMed:22841715, PubMed:25838379)
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SwissProt ID
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Synonyms
MRP-S27; S27mt
Documentation
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