Mucin 5B Antibody (YA4507)
(Synonyms: MG1; MUC5; MUC9; MUC-5B)Mucin 5B Antibody (YA4507) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 5B.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
Mucin 5B Antibody (YA4507) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 5B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 596 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 596 kDa
Purified recombinant fragment of human MUC5B (AA: 26-166) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Mucin 5B is a Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:It is expressed on the surface epithelial cells of the respiratory tract. It is mainly expressed in the mucous cells of the submucosal glands of the respiratory tract. It is highly expressed in the sublingual glands. It is also found in the submandibular glands, cervical endometrium, gallbladder, and pancreas.
Induction:Regulated by all-trans-retinoic acid (ATRA) in a cell-type specific manner -
Subunit
Homomultimer; disulfide-linked (PubMed:31570524). The N- and C-terminus mediate their assembly into higher order structures to form filaments (By similarity). The CTCK domains of two polypeptides associate in the endoplasmic reticulum to generate intermolecularly disulfide-bonded dimers (PubMed:31570524). These dimers progress to the Golgi apparatus, which is a more acidic environment than the endoplasmic reticulum (By similarity). Under acidic conditions, the N-termini form non-covalent intermolecular interactions that juxtapose assemblies from different CTCK-linked dimers to produce long, disulfide-linked polymers that remain highly compact until secretion (By similarity)
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SwissProt ID
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Synonyms
MG1; MUC5; MUC9; MUC-5B
Documentation
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