MUM1 Antibody (YA5734)

Cat. No.: HY-P86042: Data Sheet User Guide for Antibodies
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MUM1 Antibody (YA5734) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUM1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

MUM1 Antibody (YA5734) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUM1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 52 kDa;

Observed band size: 52 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q15306

Gene ID

3662 [NCBI]

Immunogen

Synthesized peptide derived from human MUM1 AA range: 350-451

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:500-5000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes

Subcellular Localization：Nucleus; Cytoplasm

Expression：
Tissue_specificity:lymphocytes

Induction:Not induced by interferons

Isoforms & Post-Translational Modification：Q15306 has 2 isomers: Q15306-1: 51772 Da (predicted); Q15306-2: 51644 Da (predicted).
Phosphorylation by ROCK2 regulates IL-17 and IL-21 production

Subunit：Interacts with SPIB (PubMed:10196196). Interacts with DEF6 (PubMed:12651066). Interacts with SPI1 (PubMed:33951726)

Synonyms

Interferon regulatory factor 4; IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5;

Documentation

User Guide for Antibodies (1077 KB)