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Neurofilament/NF-L Antibody (YA3679)

(Synonyms: NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110)
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Neurofilament/NF-L Antibody (YA3679) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Neurofilament/NF-L.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, IHC-P, FC, ELISA

  • Reactivity :

    Human, Mouse, Rat, Rabbit

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • Neurofilament/NF-L Antibody (YA3679) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:100-1:500 1:200-1:400 1:10000

Product Details

Description

Neurofilament/NF-L Antibody (YA3679) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Neurofilament/NF-L.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat, Rabbit
  • Observed Molecular Weight
    Observed band size: 72 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 62 kDa
Immunogen

Purified recombinant fragment of human NEFL (AA: 1-200) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Neurofilament/NF-L is a Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks

  • Subcellular Localization

    Cell projection, axon; Cytoplasm, cytoskeleton

  • Subunit

    Interacts with ARHGEF28. Interacts with TRIM2

  • SwissProt ID

    P07196

  • Gene ID
    4747 [NCBI]
  • Synonyms

    NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110

Neurofilament/NF-L Antibody (YA3679) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Neurofilament/NF-L Antibody (YA3679) Product Image
    1/16
  • Neurofilament/NF-L Antibody (YA3679) Product Image