NPR3 Antibody (YA9772)
(Synonyms: NPR3, Natriuretic Peptide Receptor 3, C5orf23, GUCY2B, ANPRC, NPRC, Natriuretic Peptide Receptor C/Guanylate Cyclase C (Atrionatriuretic Peptide Receptor C), Atrial Natriuretic Peptide Clearance Receptor, Atrial Natriuretic Peptide Receptor Type C, Atrial Natriuretic Peptide Receptor 3, Atrionatriuretic Peptide Receptor C, Guanylate Cyclase C, FLJ14054, ANPR-C, ANP-C, NPR-C, Chromosome 5 Open Reading Frame 23, Natriuretic Peptide Receptor C, BOMOS)NPR3 Antibody (YA9772) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to NPR3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC, ICC/IF
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Reactivity :
Human, mouse, rat
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Formulation:
Supplied in PBS (pH 7.4) containing 50% glycerol, 0.05% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:200-2000 | 1:100-1000 |
Product Details
NPR3 Antibody (YA9772) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to NPR3.
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Host Rabbit
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Species ReactivityHuman, mouse, rat
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Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 60 kDa,
A synthesized peptide derived from human Natriuretic Peptide Receptor C
affinity purified.
Non-conjugated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4) containing 50% glycerol, 0.05% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NPR3 is a Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity)
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Subcellular Localization
Cell membrane
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Isoforms & Post-Translational Modification
NPR3 has 3 isoforms, P17342-1: amino acid length is 541, molecular weight is 59808 Da (predicted); P17342-2: amino acid length is 540, molecular weight is 59767 Da (predicted); P17342-3: amino acid length is 324, molecular weight is 36656 Da (predicted).
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Subunit
Homodimer; disulfide-linked.
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SwissProt ID
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Synonyms
NPR3, Natriuretic Peptide Receptor 3, C5orf23, GUCY2B, ANPRC, NPRC, Natriuretic Peptide Receptor C/Guanylate Cyclase C (Atrionatriuretic Peptide Receptor C), Atrial Natriuretic Peptide Clearance Receptor, Atrial Natriuretic Peptide Receptor Type C, Atrial Natriuretic Peptide Receptor 3, Atrionatriuretic Peptide Receptor C, Guanylate Cyclase C, FLJ14054, ANPR-C, ANP-C, NPR-C, Chromosome 5 Open Reading Frame 23, Natriuretic Peptide Receptor C, BOMOS
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