NRF-1 Antibody (YA5891)
(Synonyms: NRF1; Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal)
Based on 1 Customer Validation
NRF-1 Antibody (YA5891) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRF-1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IP, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:2000-1:10000 | 1:200-1:1000 | 1:5000-1:20000 | 1:50-1:200 |
Product Details
NRF-1 Antibody (YA5891) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRF-1.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 68 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 54 kDa
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NRF-1 transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:It is widely expressed, with the strongest expression in skeletal muscle. -
Isoforms & Post-Translational Modification
Q16656 has 4 isomers: Q16656-1: 53541 Da (predicted); Q16656-2: 46157 Da (predicted); Q16656-3: 36051 Da (predicted); Q16656-4: 55674 Da (predicted).
Phosphorylation enhances DNA binding -
Subunit
Homodimer. Binds DNA as a dimer. Interacts with PPRC1
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SwissProt ID
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Synonyms
NRF1; Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal
Documentation
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