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Cat. No.: HY-P84792A

P2RY12 Antibody (YA4489)(PBS only)

Name: P2RY12 Antibody (YA4489)(PBS only)
Brand: MedChemExpress
SKU: HY-P84792A
Availability: PreOrder

(Synonyms: HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc))

P2RY12 Antibody (YA4489) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P2RY12.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	FC FC: Flow Cytometry	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-1:2000	1:200-1:400	1:10000

Description

P2RY12 Antibody (YA4489) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P2RY12.

Host Mouse
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 52 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 39 kDa

Immunogen

Purified recombinant fragment of human P2RY12 (AA: extra mix) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

P2RY12 receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation
Subcellular Localization

Cell membrane; Multi-pass membrane protein
Expression

Tissue_specificity:It is highly expressed in platelets and less so in brain tissue. It is expressed at the lowest levels in the lungs, appendix, pituitary gland, and adrenal glands. It is also expressed in the spinal cord and fetal brain tissue.
SwissProt ID

Q9H244
Gene ID

64805 [NCBI]
Synonyms

HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)