PDLIM5 Antibody (YA8121)(PBS only)

Cat. No.: HY-P88437A: Data Sheet User Guide for Antibodies
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PDLIM5 Antibody (YA8121) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PDLIM5.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PDLIM5 Antibody (YA8121) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PDLIM5.

Host

Mouse

Molecular Weight

Predicted band size: 63.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q96HC4

Immunogen

Full length human recombinant protein of human PDLIM5 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation

Subcellular Localization：Postsynaptic density,Presynapse,Postsynapse,Cytoplasm, cytosol

Expression：
Tissue_Specificity: Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression

Isoforms & Post-Translational Modification：Q96HC4 has 7 isomers: Q96HC4-1: 63945 Da (predicted); Q96HC4-2: 25930 Da (predicted); Q96HC4-3: 23823 Da (predicted); Q96HC4-4: 53078 Da (predicted); Q96HC4-5: 15116 Da (predicted); Q96HC4-6: 67729 Da (predicted); Q96HC4-7: 52645 Da (predicted).

Subunit：Interacts with various PKC isoforms through the LIM domains

Synonyms

ENH; ENH1; L9; LIM

Documentation

User Guide for Antibodies (1077 KB)