PIN4 Antibody (YA7671)
(Synonyms: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Parvulin-17, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, Rotamase Pin4, Par14, hPar14, Par17, hPar17, PPIase Pin4, hEPVH, PIN4)
Based on 1 Customer Validation
PIN4 Antibody (YA7671) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PIN4.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:100-500 | 1:50-100 |
Product Details
PIN4 Antibody (YA7671) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PIN4.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman, Mouse, Rat Predicted Reactivity: Mouse,Rat
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 13 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 14 kDa
A synthesized peptide derived from human PIN4: 100-131.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PIN4 is an Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA|Isoform 2 binds to double-stranded DNA
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Subcellular Localization
Nucleus, nucleolus,Cytoplasm, cytoskeleton, spindle,Cytoplasm,Mitochondrion,Mitochondrion matrix
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Expression
Tissue_Specificity: Isoform 2 is much more stable than isoform 1 (at protein level). Ubiquitous. Isoform 1 and isoform 2 are expressed in kidney, liver, blood vessel, brain, mammary gland, skeletal muscle, small intestine and submandibularis. Isoform 1 transcripts are much more abundant than isoform 2 in each tissue analyzed -
Isoforms & Post-Translational Modification
Q9Y237 has three isomers: Q9Y237-1: 13810 Da (predicted); Q9Y237-2: 16608 Da (predicted); Q9Y237-3: 14179 Da (predicted).
Phosphorylated丨Isoform 2 is sumoylated with SUMO2 and SUMO3 -
Subunit
Isoform 1 is found in pre-ribosomal ribonucleoprotein (pre-rRNP) complexes
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SwissProt ID
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Synonyms
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Parvulin-17, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, Rotamase Pin4, Par14, hPar14, Par17, hPar17, PPIase Pin4, hEPVH, PIN4
Documentation
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