POFUT2 Antibody (YA8583)(PBS only)

Cat. No.: HY-P88899A: Data Sheet User Guide for Antibodies
FAQs
Technical Support

POFUT2 Antibody (YA8583) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to POFUT2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

POFUT2 Antibody (YA8583) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to POFUT2.

Host

Mouse

Molecular Weight

Predicted band size: 49.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y2G5

Immunogen

Full length human recombinant protein of human POFUT2 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively (PubMed:22588082). O-fucosylates members of several protein families including the ADAMTS, the thrombospondin (TSP) and spondin families (Probable) (PubMed:17395588). Required for the proper secretion of ADAMTS family members such as ADAMTSL1 and ADAMTS13 (PubMed:17395588, PubMed:17395589). The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm (By similarity)

Subcellular Localization：Endoplasmic reticulum,Golgi apparatus

Expression：
Tissue_Specificity: Isoform A is expressed in fetal liver and peripheral blood lymphocytes. Isoform B is expressed in spleen, lung, testis, bone marrow, thymus, pancreas, prostate, fetal brain, fetal liver and fetal kidney. Isoform C is expressed in brain, heart, spleen, liver, lung, stomach, testis, placenta, skin, thymus, pancreas, mammary gland, prostate, fetal brain, fetal liver and fetal heart

Isoforms & Post-Translational Modification：Q9Y2G5 has three isomers: Q9Y2G5-3: 49976 Da (predicted); Q9Y2G5-1: 48896 Da (predicted); Q9Y2G5-2: 44083 Da (predicted).

Synonyms

C21orf80; FUT13

Documentation

User Guide for Antibodies (1077 KB)