2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. PSF1 Antibody (YA1763)

PSF1 Antibody (YA1763) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PSF1.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

  • Referencias

Descripciòn

PSF1 Antibody (YA1763) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PSF1.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Peso molecular
Predicted band size: 23 kDa;
Observed band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human PSF1 aa152-164.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:5000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:100
FC
FC: Flow Cytometry
1:50-1:100
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks (PubMed:17417653, PubMed:28414293). GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built (PubMed:32453425, PubMed:34694004, PubMed:34700328, PubMed:35585232)
Subcellular Localization：Nucleus; Chromosome
Expression：
Induction:Significantly up-regulated in aggressive melanomas
Subunit：Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4 (PubMed:17545466, PubMed:17557111, PubMed:17652513, PubMed:28414293). Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro (PubMed:17545466, PubMed:17557111, PubMed:17652513, PubMed:28414293). Component of the CMG helicase complex, a hexameric ring of related MCM2-7 subunits stabilized by CDC45 and the tetrameric GINS complex (PubMed:32453425, PubMed:34694004, PubMed:34700328)
Database

Entrez Gene: 9837 Human ; 69270 Mouse ; 499914 Rat

SwissProt: Q14691 Human ; Q9CZ15 Mouse ;

OMIM: 617827 Human

Research Field

Epigenetics and Nuclear Signaling
Synonyms
GINS complex subunit 1
Documentación
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)
Referencias

PSF1 Antibody (YA1763) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
PSF1 Antibody (YA1763)
Cat. No.:
HY-P82018
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SAFETY DATA SHEET (SDS)

English - EN (251 KB)

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