PTPN14 Antibody (YA6998)

製品番号: HY-P87315: データシート User Guide for Antibodies
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PTPN14 Antibody (YA6998) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPN14.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

PTPN14 Antibody (YA6998) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPN14.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 135 kDa;

Observed band size: 135 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q15678

Immunogen

Purified recombinant fragment of human PTPN14 (AA: 896-1169) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200
FC FC: Flow Cytometry	1:50-1:100

Sensitivity	Endogenous	純度	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in in PBS with 0.05% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor

Subcellular Localization：Cytoplasm,Cytoplasm, cytoskeleton,Nucleus

Expression：
Tissue_Specificity: Ubiquitous
Induction: Up-regulated at protein level by cell density. However, at the mRNA level remains the same regardless of the status of cell density

Subunit：Interacts with FLT4; the interaction is enhanced by stimulation with VEGFC

Synonyms

Cytoskeletal associated protein tyrosine phosphatase antibody; MGC126803 antibody; PEZ antibody; Phosphatase with ezrin domain antibody; Protein tyrosine phosphatase non receptor type 14 antibody; Protein tyrosine phosphatase pez antibody; Protein-tyrosine phosphatase pez antibody; PTN14_HUMAN antibody; PTP 36 antibody; PTP36 antibody

ドキュメンテーション

User Guide for Antibodies (1077 KB)

PTPN14 Antibody (YA6998) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PTPN14 Antibody (YA6998)

Product Detail

Background

説明

PTPN14 Antibody (YA6998) 関連分類

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