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PYCR2 Antibody (YA7952)(PBS only)

(Synonyms: HLD10; P5CR2)

PYCR2 Antibody (YA7952) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYCR2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    WB, IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PYCR2 Antibody (YA7952)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-2000 1:150-500 1:100-250 1:100

Product Details

Description

PYCR2 Antibody (YA7952) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYCR2.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 33.5 kDa
Immunogen

Full length human recombinant protein of human PYCR2 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PYCR2 is an Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+)[1][2][3][4].

  • Subcellular Localization

    Cytoplasm,Mitochondrion

  • Expression


    Tissue_Specificity: Detected in erythrocytes (at protein level) (PubMed:2722838, PubMed:6894153). Expressed in fetal brain (PubMed:25865492)

  • Isoforms & Post-Translational Modification

    Q96C36: 320 amino acids, molecular weight 33637 Da.

  • Subunit

    Homodecamer; composed of 5 homodimers (Probable)

  • SwissProt ID

    Q96C36

  • Synonyms

    HLD10; P5CR2

PYCR2 Antibody (YA7952)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PYCR2 Antibody (YA7952)(PBS only) Product Image
    1/16
  • PYCR2 Antibody (YA7952)(PBS only) Product Image