PYCRL Antibody (YA8446)
(Synonyms: PYCR3)PYCRL Antibody (YA8446) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYCRL.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:150-500 | 1:100-250 | 1:100 |
Product Details
PYCRL Antibody (YA8446) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYCRL.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 28.5 kDa
Full length human recombinant protein of human PYCRL produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PYCRL is an Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate (P5C) to L-proline using NAD(P)H. Proline is synthesized from either glutamate or ornithine; both are converted to P5C, and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCR3 is exclusively linked to the biosynthesis of proline from ornithine[1][2].
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
Q53H96 has two isomers: Q53H96-1: 28663 Da (predicted); Q53H96-2: 26440 Da (predicted).
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Subunit
Homodecamer; composed of 5 homodimers
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SwissProt ID
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Synonyms
PYCR3
Documentation
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