RAB23 Antibody (YA7168)
(Synonyms: HSPC137, RAB23, Ras-related protein Rab-23)RAB23 Antibody (YA7168) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB23.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, FC, ELISA
-
Reactivity :
Mouse
-
Formulation:
Supplied in PBS (pH 7.4) containing 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:200-2000 | 1:5000-10000 |
Product Details
RAB23 Antibody (YA7168) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB23.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityMouse
-
Observed Molecular WeightObserved band size: 26kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 26kDa
Recombinant protein of human RAB23.
Endogenous
affinity purified by Protein G
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4) containing 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
RAB23 is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes
-
Subcellular Localization
Cell membrane,Cytoplasm,Cytoplasmic vesicle, autophagosome,Endosome membrane,Cytoplasmic vesicle, phagosome,Cytoplasmic vesicle, phagosome membrane
-
Isoforms & Post-Translational Modification
Q9ULC3: 237 amino acids, molecular weight 26659 Da.
-
Subunit
Interacts with SUFU
-
SwissProt ID
-
Synonyms
HSPC137, RAB23, Ras-related protein Rab-23
Documentation
Powered by Bioz
