RAB23 Antibody (YA7168)

Cat. No.: HY-P87481: Data Sheet User Guide for Antibodies
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RAB23 Antibody (YA7168) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB23.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

RAB23 Antibody (YA7168) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB23.

Host

Mouse

Clonality

Monoclonal,Recombinant

Molecular Weight

Predicted band size: 23kDa;

Species Reactivity

Mouse

SwissProt ID

Q9ULC3

Immunogen

Recombinant human RAB23 (Fragment) (His-tagged).

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
FC FC: Flow Cytometry	1:25
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-10000

Sensitivity	Endogenous	Purity	affinity purified by Protein G
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes

Subcellular Localization：Cell membrane,Cytoplasm,Cytoplasmic vesicle, autophagosome,Endosome membrane,Cytoplasmic vesicle, phagosome,Cytoplasmic vesicle, phagosome membrane

Isoforms & Post-Translational Modification：Q9ULC3: 237 amino acids, molecular weight 26659 Da.

Subunit：Interacts with SUFU

Documentation

User Guide for Antibodies (1077 KB)