RAB30 Antibody (YA8262)
(Synonyms: member RAS oncogene family; RAB30)RAB30 Antibody (YA8262) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB30.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100 |
Product Details
RAB30 Antibody (YA8262) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB30.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 22.9 kDa
Full length human recombinant protein of human RAB30 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RAB30 is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB30 is required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins. Facilitates lipid homeostasis during fasting by regulating hepatic protein and lipid trafficking in a PPAR-alpha-dependent manner. Promotes autophagosome biogenesis during bacterial infection such as group A Streptococcus infection[1][2].
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Subcellular Localization
Membrane,Golgi apparatus, trans-Golgi network membrane,Golgi apparatus, cis-Golgi network membrane,Golgi apparatus membrane,Cytoplasm,Cytoplasmic vesicle, autophagosome membrane,Autolysosome membrane
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Isoforms & Post-Translational Modification
Q15771 has two isomers: Q15771-1: 23058 Da (predicted); Q15771-2: 18994 Da (predicted).
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SwissProt ID
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Synonyms
member RAS oncogene family; RAB30
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