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RBBP9 Antibody (YA8223)(PBS only)

(Synonyms: BOG; RBBP10)

RBBP9 Antibody (YA8223) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RBBP9.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • RBBP9 Antibody (YA8223)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

RBBP9 Antibody (YA8223) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RBBP9.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 20.8 kDa
Immunogen

Full length human recombinant protein of human RBBP9 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RBBP9 serine hydrolase (Probable). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1[1][2][3].

  • Expression


    Tissue_Specificity: Expressed at higher levels in tumor tissues such as carcinoma

  • Isoforms & Post-Translational Modification

    O75884 has two isomers: O75884-1: 21000 Da (predicted); O75884-2: 19394 Da (predicted).

  • Subunit

    Interacts with RB1; the interaction disrupts RB1 binding to E2F1 (PubMed:21689726)

  • SwissProt ID

    O75884

  • Synonyms

    BOG; RBBP10

RBBP9 Antibody (YA8223)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • RBBP9 Antibody (YA8223)(PBS only) Product Image
    1/16
  • RBBP9 Antibody (YA8223)(PBS only) Product Image