RBBP9 Antibody (YA8223)
(Synonyms: BOG; RBBP10)RBBP9 Antibody (YA8223) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RBBP9.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
RBBP9 Antibody (YA8223) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RBBP9.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 20.8 kDa
Full length human recombinant protein of human RBBP9 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RBBP9 serine hydrolase (Probable). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1[1][2][3].
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Expression
Tissue_Specificity: Expressed at higher levels in tumor tissues such as carcinoma -
Isoforms & Post-Translational Modification
O75884 has two isomers: O75884-1: 21000 Da (predicted); O75884-2: 19394 Da (predicted).
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Subunit
Interacts with RB1; the interaction disrupts RB1 binding to E2F1 (PubMed:21689726)
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SwissProt ID
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Synonyms
BOG; RBBP10
Documentation
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