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RBFOX2 Antibody (YA3534)(PBS only)

(Synonyms: RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3)

RBFOX2 Antibody (YA3534) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBFOX2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • RBFOX2 Antibody (YA3534)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

RBFOX2 Antibody (YA3534) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBFOX2.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 43 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 41.4 kDa
Immunogen

Purified recombinant fragment of human RBFOX2 (AA: 1-145) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RBFOX2 is a RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. Together with RNA binding proteins RBPMS and MBNL1/2, activates vascular smooth muscle cells alternative splicing events[1].

  • Subcellular Localization

    Nucleus; Cytoplasm

  • Isoforms & Post-Translational Modification

    O43251 has 10 isomers: O43251-1: 41374 Da (predicted); O43251-2: 40479 Da (predicted); O43251-3: 37879 Da (predicted); O43251-4: 39783 Da (predicted); O43251-5: 39954 Da (predicted); O43251-6: 47215 Da (predicted); O43251-7: 43179 Da (predicted); O43251-8: 47343 Da (predicted); O43251-9: 39515 Da (predicted); O43251-10: 40351 Da (predicted).

  • Subunit

    Interacts with ER-alpha N-terminal activation domain. Interacts with RBPMS; the interaction allows cooperative assembly of stable cell-specific alternative splicing regulatory complexes (PubMed:37548402)

  • SwissProt ID

    O43251

  • Gene ID
    23543 [NCBI]
  • Synonyms

    RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3

RBFOX2 Antibody (YA3534)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • RBFOX2 Antibody (YA3534)(PBS only) Product Image