S-100A14 Antibody (YA8880)
(Synonyms: S100A15, S100A14, Protein S100-A14, S100 calcium-binding protein A14, S114)
Based on 1 Customer Validation
S-100A14 Antibody (YA8880) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to S-100A14.
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Host:
Mouse
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Isotype:
IgG
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Application:
ICC/IF, IF-Tissue, IHC-P, ELISA
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:50-500 | 1:50-500 | 1:100-500 | 1:50-3000 |
Product Details
S-100A14 Antibody (YA8880) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to S-100A14.
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Host Mouse
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Species Reactivityhuman
OMIM: 607986
A synthesized peptide derived from human S-100A14.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
S-100A14 modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes. -
Isoforms & Post-Translational Modification
S-100A14 has an amino acid length of 104, molecular weight is 11662 Da.
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Subunit
Homodimer.
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SwissProt ID
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Synonyms
S100A15, S100A14, Protein S100-A14, S100 calcium-binding protein A14, S114
Documentation
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