SA2 Antibody (YA7640)

Cat. No.: HY-P87955: Data Sheet User Guide for Antibodies
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SA2 Antibody (YA7640) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SA2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

SA2 Antibody (YA7640) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SA2.

Host

Rabbit

Clonality

Recombinant

Molecular Weight

Predicted band size: 141 kDa;

Observed band size: 141 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse Predicted Reactivity: Rat

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

Q8N3U4

Immunogen

A synthesized peptide derived from human Cohesin subunit SA 2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-200
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-200
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:50-200
FC FC: Flow Cytometry	1:50-100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200

Sensitivity	Endogenous	Purity	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis

Subcellular Localization：Nucleus,Chromosome,Chromosome, centromere

Isoforms & Post-Translational Modification：Q8N3U4 has two isomers: Q8N3U4-1: 141326 Da (predicted); Q8N3U4-2: 145751 Da (predicted).
Phosphorylated by PLK1

Subunit：Interacts directly with RAD21 in cohesin complex

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/u-937-cell.html [Content Brief]