SAMD9 Antibody (YA1901)(PBS only)
(Synonyms: SAM domain-containing protein 9)SAMD9 Antibody (YA1901) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SAMD9.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:50-1:100 | 1:20-1:50 |
Product Details
SAMD9 Antibody (YA1901) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SAMD9.
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Host Rabbit
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 184 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 184 kDa
A synthetic peptide of human SAMD9 aa 84-189.
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SAMD9 is a Double-stranded nucleic acid binding that acts as an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules. May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion[1][2].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_specificity:Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from with normophosphatemic tumoral calcinosis (NFTC)
Induction:Up-regulated by TNF-alpha through p38 MAPKs and NF-kappa-B. Up-regulated by osmotic shock. Induced by IFNG -
Subunit
Interacts with RGL2 (PubMed:21160498). Interacts with EEA1 (PubMed:24029230)
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SwissProt ID
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Synonyms
SAM domain-containing protein 9
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Research Field
Cell Biology
Documentation
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