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  4. SLC27A5 Antibody (YA4586)

SLC27A5 Antibody (YA4586) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC27A5.

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容量 価格(税別) 在庫状況 数量
10 μL $96 在庫あり
50 μL $252 在庫あり
100 μL $408 在庫あり
250 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • 説明

  • 参考文献

製品説明

SLC27A5 Antibody (YA4586) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC27A5.

Host

Mouse

Clonality

Monoclonal Antibody

分子量
Predicted band size: 75 kDa;
Observed band size: 75 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Gene ID
Immunogen

Purified recombinant fragment of human SLC27A5 (AA: 508-570) expressed in E. Coli.

Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:200-1:1000
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
純度 affinity purified. Conjugation Non-conjugated
Modification Unmodified Isotype IgG1
Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background
Function:May mediate the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes (PubMed:20448275, PubMed:20530735). Also catalyzes the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:10479480). Mainly functions as a bile acyl-CoA synthetase catalyzing the activation of bile acids via ATP-dependent formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine (PubMed:10749848, PubMed:11980911). Both primary bile acids (cholic acid and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic acid) are the principal substrates (PubMed:10749848, PubMed:11980911). In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate ((25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate or THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol (PubMed:11980911). Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids (By similarity)
Subcellular Localization:Endoplasmic reticulum membrane; Multi-pass membrane protein; Microsome; Cell membrane; Multi-pass membrane protein
Expression:
Tissue_specificity:Predominantly expressed in liver
Isoforms & Post-Translational Modification:Q9Y2P5 has 2 isomers: Q9Y2P5-1: 75385 Da (predicted); Q9Y2P5-2: 66846 Da (predicted).
RRID
Synonyms
BAL; ACSB; BACS; FATP5; ACSVL6; FACVL3; FATP-5; VLACSR; VLCSH2; VLCS-H2
ドキュメンテーション
参考文献

SLC27A5 Antibody (YA4586) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
SLC27A5 Antibody (YA4586)
製品番号:
HY-P84889
数量:
MCE 日本正規代理店: