SLP2 Antibody (YA1720)

製品番号: HY-P81975: データシート SDS COA User Guide for Antibodies
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SLP2 Antibody (YA1720) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLP2.

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容量	価格（税別）	在庫状況	数量
20 μL	$146	在庫あり	Estimated Time of Arrival: December 31
50 μL	$222	在庫あり	Estimated Time of Arrival: December 31
100 μL	$360	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

SLP2 Antibody (YA1720) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLP2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

分子量

Predicted band size: 39 kDa;

Observed band size: 39 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9UJZ1

Gene ID

30968 [NCBI]

Immunogen

A synthetic peptide of human STOML2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:500
FC FC: Flow Cytometry	1:200-1:1000
IP IP: Immunoprecipitation	1:20-1:50

Sensitivity	Endogenous	純度	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation

Subcellular Localization：Cell membrane; Peripheral membrane protein; Mitochondrion; Mitochondrion inner membrane; Lipid-anchor; Mitochondrion intermembrane space; Membrane raft; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:Ubiquitously expressed at low levels. Expressed in lymphoid tissues (at protein level)

Induction:Up-regulated in activated B- and T-cells and upon mitochondrial stress by chloramphenicol

Isoforms & Post-Translational Modification：Q9UJZ1 has 2 isomers: Q9UJZ1-1: 38534 Da (predicted); Q9UJZ1-2: 33337 Da (predicted).
Hyperphosphorylated at Ser-17 in some patients with monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM) and Waldenstrom macroglobulinemia due to impaired dephosphorylation by PP2A

Subunit：Forms homooligomers. Interacts with MFN2; may form heterooligomers.

Database

Entrez Gene: 30968 Human ; 66592 Mouse ; 298203 Rat

SwissProt: Q9UJZ1 Human ; Q99JB2 Mouse ; Q4FZT0 Rat

OMIM: 608292 Human

Research Field

Cancer

Synonyms

stomatin like 2; SLP-2; HSPC108

ドキュメンテーション

Select Batch:

データシート (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/bel-7402-cell.html [Content Brief]