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SMC4 Antibody (YA2340)

(Synonyms: CAPC; hCAP C; hCAP-C; SMC 4; SMC4; SMC4L1; XCAP C homolog)
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SMC4 Antibody (YA2340) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SMC4.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, FC

  • Reactivity :

    Human, Mouse

  • Formulation:

    Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Conjugation:
    Non-conjugated
  • SMC4 Antibody (YA2340) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:1000-1:2000 1:50-1:200 1:50-1:100

Product Details

Description

SMC4 Antibody (YA2340) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SMC4.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse
  • Observed Molecular Weight
    Observed band size: 160 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 147 kDa
Species Reactivity Database
Immunogen

A synthesized peptide derived from human SMC4 aa1200-1250.

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SMC4 is a Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases

  • Subcellular Localization

    Nucleus; Cytoplasm; Chromosome

  • Expression


    Tissue_specificity:Widely expressed. Higher expression in testis, colon, thymus

  • Isoforms & Post-Translational Modification

    Q9NTJ3 has 2 isomers: Q9NTJ3-1: 147182 Da (predicted); Q9NTJ3-2: 140278 Da (predicted).

  • Subunit

    Forms a heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG

  • SwissProt ID

    Q9NTJ3

  • Gene ID
    10051 [NCBI]
  • Synonyms

    CAPC; hCAP C; hCAP-C; SMC 4; SMC4; SMC4L1; XCAP C homolog

  • Research Field

    Cell Biology

SMC4 Antibody (YA2340) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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