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SOD2 Antibody (YA3635)(PBS only)

(Synonyms: IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD)

SOD2 Antibody (YA3635) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOD2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, IHC-P, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • SOD2 Antibody (YA3635)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

SOD2 Antibody (YA3635) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOD2.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 22 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 25 kDa
Immunogen

Purified recombinant fragment of human SOD2 (AA: 1-222) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SOD2 is a Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems

  • Subcellular Localization

    Mitochondrion matrix

  • Expression


    Induction:Expression is regulated by KRIT1

  • Isoforms & Post-Translational Modification

    P04179 has 4 isomers: P04179-1: 24750 Da (predicted); P04179-2: 20724 Da (predicted); P04179-3: 18262 Da (predicted); P04179-4: 19730 Da (predicted).
    Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity;Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity);Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability

  • Subunit

    Homotetramer

  • SwissProt ID

    P04179

  • Gene ID
    6648 [NCBI]
  • Synonyms

    IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD

SOD2 Antibody (YA3635)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • SOD2 Antibody (YA3635)(PBS only) Product Image