SOX11 Antibody (YA3976)
(Synonyms: CSS9; MRD27)Based on 1 Customer Validation
SOX11 Antibody (YA3976) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOX11.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, IHC-P, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
SOX11 Antibody (YA3976) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOX11.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 60-80 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 47 kDa
Purified recombinant fragment of human SOX11 (AA: 1-250) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS with 0.05% sodium azide
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
SOX11 transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis[1][2].
-
Subcellular Localization
Nucleus
-
Expression
Tissue_specificity:It is primarily expressed in the brain and heart, with lower levels of expression in the kidneys, pancreas, and muscles. -
SwissProt ID
-
Synonyms
CSS9; MRD27
Documentation