SRSF7 Antibody
(Synonyms: SFRS7, SRSF7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8)SRSF7 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to SRSF7.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
SRSF7 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to SRSF7.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 35 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 27 kDa
Synthetic peptide corresponding to the center region of human SRSF7.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SRSF7 is required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific
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Subcellular Localization
Nucleus; Cytoplasm
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Expression
Tissue_Specificity: Brain, liver, kidney and lung. -
Isoforms & Post-Translational Modification
SRSF7 has 4 isoforms, Q16629-1: amino acid length is 238, molecular weight is 27367 Da (predicted); Q16629-2: amino acid length is 135, molecular weight is 15573 Da (predicted); Q16629-3: amino acid length is 132, molecular weight is 15257 Da (predicted); Q16629-4: amino acid length is 226, molecular weight is 26012 Da (predicted).
Extensively phosphorylated on serine residues in the RS domain. -
Subunit
Found in large molecular weight complexes containing CCNL1 and the p110 isoforms of either CDC2L1 or CDC2L2.
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SwissProt ID
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Synonyms
SFRS7, SRSF7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8
Documentation
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