SYT1 Antibody (YA7119)
SYT1 Antibody (YA7119) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYT1.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, IHC-P, FC, ELISA
-
Reactivity :
Human, Mouse, Rat, Rabbit
-
Formulation:
Supplied in Ascitic fluid containing 0.03% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
SYT1 Antibody (YA7119) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYT1.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Mouse, Rat, Rabbit
-
Calculated Molecular Weight Predicted band size: 48kDa;
SwissProt: SwissProt: P21579 ; SwissProt: P46096 ; SwissProt: P21707 ; Rabbit: G1U4K2
Purified recombinant fragment of SYT1 expressed in E. Coli.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in Ascitic fluid containing 0.03% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
SYT1 is a Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes[1].
-
Subcellular Localization
Cytoplasmic vesicle, secretory vesicle membrane,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane,Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane,Cytoplasm
-
Expression
Tissue_Specificity: Expressed in melanocytes (PubMed:23999003) -
Isoforms & Post-Translational Modification
P21579: 422 amino acids, molecular weight 47573 Da.
-
Subunit
Homotetramer (Probable)
-
SwissProt ID
Documentation
Powered by Bioz
