TACI Antibody (YA1385)
(Synonyms: CD267; TACI; TNFRSF13B)TACI Antibody (YA1385) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TACI.
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Host:
Rabbit
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Isotype:
IgG
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Conjugation:
Non-conjugated
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Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:50-1:100 | 1:10000 |
Product Details
TACI Antibody (YA1385) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TACI.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 32 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
Recombinant human TACI protein
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TACI receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity
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Subcellular Localization
Membrane; Single-pass type III membrane protein
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Expression
Tissue_specificity:It is highly expressed in the spleen, thymus, small intestine, and peripheral blood leukocytes. It is expressed in resting B cells and activated T cells, but not in resting T cells. -
Isoforms & Post-Translational Modification
O14836 has 3 isomers: O14836-1: 31816 Da (predicted); O14836-2: 26664 Da (predicted); O14836-3: 19865 Da (predicted).
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Subunit
Binds TRAF2, TRAF5 and TRAF6. Binds the NH2-terminal domain of CAMLG with its C-terminus
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SwissProt ID
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Synonyms
CD267; TACI; TNFRSF13B
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Research Field
Immunology
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