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Thyroid Hormone Receptor beta/THRB Antibody (YA7135)

(Synonyms: ERBA2, NR1A2, THR1, THRB, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta)
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Thyroid Hormone Receptor beta/THRB Antibody (YA7135) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Thyroid Hormone Receptor beta/THRB.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IHC-F, IF-Tissue, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

  • Conjugation:
    Non-conjugated
  • Thyroid Hormone Receptor beta/THRB Antibody (YA7135) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
IHC-F Info
IHC-F: Immunohistochemistry-Frozen
IF-Tissue Info
IF-Tissue: Immunofluorescence-Tissue
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-2000 1:100-500 1:400-800 1:100-500 1ug/Test

Product Details

Description

Thyroid Hormone Receptor beta/THRB Antibody (YA7135) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Thyroid Hormone Receptor beta/THRB.

  • Host Mouse
  • Clonality Monoclonal,Recombinant
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 53kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 53kDa
Immunogen

Recombinant human THRB protein: 209-461/461.

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Thyroid Hormone Receptor beta/THRB is a Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    P10828 has two isomers: P10828-1: 52788 Da (predicted); P10828-2: 54449 Da (predicted).

  • Subunit

    Binds DNA as a dimer; homodimer and heterodimer with RXRA

  • SwissProt ID

    P10828

  • Synonyms

    ERBA2, NR1A2, THR1, THRB, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta

Thyroid Hormone Receptor beta/THRB Antibody (YA7135) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • Thyroid Hormone Receptor beta/THRB Antibody (YA7135) Product Image