DcR2 Antibody (YA4552)
(Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4)DcR2 Antibody (YA4552) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DcR2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ELISA
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Reactivity :
Human, Monkey
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
DcR2 Antibody (YA4552) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DcR2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Monkey
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Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 42 kDa
Purified recombinant fragment of human TNFRSF10D (AA: extra 56-211) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DcR2 receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to, it cannot but according to, it can induce the NF-kappa-B pathway[1][2][3].
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:This gene is widely expressed, especially in the fetal kidneys, lungs, and liver, as well as in the human testes and liver. It is also expressed in peripheral blood leukocytes, the colon and small intestine, ovaries, prostate, thymus, spleen, pancreas, kidneys, lungs, placenta, and heart. -
SwissProt ID
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Synonyms
DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4
Documentation
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