TPRKB Antibody (YA8488)(PBS only)

Cat. No.: HY-P88804A: Data Sheet User Guide for Antibodies
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TPRKB Antibody (YA8488) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TPRKB.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

TPRKB Antibody (YA8488) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TPRKB.

Host

Mouse

분자량

Predicted band size: 19.5 kDa

Species Reactivity

Human, Monkey, Mouse

SwissProt ID

Q9Y3C4

Immunogen

Full length human recombinant protein of human TPRKB produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:28805828). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:28805828). TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (PubMed:22912744, PubMed:28805828)

Subcellular Localization：Cytoplasm, cytosol,Nucleus

Expression：
Tissue_Specificity: Widely expressed

Isoforms & Post-Translational Modification：Q9Y3C4 has three isomers: Q9Y3C4-1: 19661 Da (predicted); Q9Y3C4-2: 16093 Da (predicted); Q9Y3C4-3: 23854 Da (predicted).

Subunit：Component of the EKC/KEOPS complex composed of at least GON7, TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes (PubMed:22912744, PubMed:28805828)

Synonyms

CGI-121; CGI121

각종 서류

User Guide for Antibodies (1077 KB)