TRP2/DCT Antibody (YA5392)
(Synonyms: L-dopachrome tautomerase; DCT; DT; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2; )
Based on 1 Customer Validation
TRP2/DCT Antibody (YA5392) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TRP2/DCT.
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Host:
Mouse
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Application:
IHC-P, WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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WB
WB: Western Blot
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|---|---|---|
| Dilution Ratio | 1:50-200 | 1:1000-2000 |
Product Details
TRP2/DCT Antibody (YA5392) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TRP2/DCT.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 60 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Synthesized peptide derived from human TRP2 DCT
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TRP2/DCT plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA)[1].
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Subcellular Localization
Melanosome membrane; Single-pass type I membrane protein; Melanosome
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Expression
Induction:Induced by blue light (415nm) -
Isoforms & Post-Translational Modification
P40126 has 2 isomers: P40126-1: 59145 Da (predicted); P40126-2: 62929 Da (predicted).
Glycosylated -
Subunit
Forms an OPN3-dependent complex with TYR in response to blue light in melanocytes
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SwissProt ID
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Synonyms
L-dopachrome tautomerase; DCT; DT; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2;
Documentation
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