TSPAN33 Antibody (YA4356)
(Synonyms: PEN; PEN.; TSPAN-33)TSPAN33 Antibody (YA4356) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TSPAN33.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
TSPAN33 Antibody (YA4356) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TSPAN33.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 64-72 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
Purified recombinant fragment of human TSPAN33 (AA:Extra(46-64)+Extra(118-235) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TSPAN33 multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity
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Subcellular Localization
Nucleus; Nucleus, nucleolus; Nucleus, nucleoplasm
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Subunit
Oligomer. The oligomeric structure enables to interact simultaneously with two separate DNA fragments. Interacts with BAZ2A/TIP5. Interacts with CAVIN1. Interacts (via the N-terminal region (NRD) and a C-terminal region) with CDKN2A/ARF; the interaction is direct. Interacts (via C-terminal region) with NPM1/B23
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SwissProt ID
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Synonyms
PEN; PEN.; TSPAN-33
Documentation
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