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UBXN2B Antibody (YA8342)(PBS only)

(Synonyms: p37)

UBXN2B Antibody (YA8342) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBXN2B.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    FC

  • Reactivity :

    Human, Dog, Monkey, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • UBXN2B Antibody (YA8342)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
FC Info
FC: Flow Cytometry
Dilution Ratio 1:100

Product Details

Description

UBXN2B Antibody (YA8342) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBXN2B.

  • Host Mouse
  • Species Reactivity
    Human, Dog, Monkey, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 36.9 kDa
Immunogen

Full length human recombinant protein of human UBXN2B produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    UBXN2B is an Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis[1][2].

  • Subcellular Localization

    Nucleus,Cytoplasm, cytosol,Endoplasmic reticulum,Golgi apparatus,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

  • Isoforms & Post-Translational Modification

    Q14CS0: 331 amino acids, molecular weight 37077 Da.

  • Subunit

    Interacts with VCP

  • SwissProt ID

    Q14CS0

  • Synonyms

    p37

UBXN2B Antibody (YA8342)(PBS only) Related Classifications

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Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • UBXN2B Antibody (YA8342)(PBS only) Product Image
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  • UBXN2B Antibody (YA8342)(PBS only) Product Image