UBXN2B Antibody (YA8342)
(Synonyms: p37)UBXN2B Antibody (YA8342) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBXN2B.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC
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Reactivity :
Human, Dog, Monkey, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 1:100 |
Product Details
UBXN2B Antibody (YA8342) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBXN2B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Dog, Monkey, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 36.9 kDa
Full length human recombinant protein of human UBXN2B produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
UBXN2B is an Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis[1][2].
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Subcellular Localization
Nucleus,Cytoplasm, cytosol,Endoplasmic reticulum,Golgi apparatus,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
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Isoforms & Post-Translational Modification
Q14CS0: 331 amino acids, molecular weight 37077 Da.
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Subunit
Interacts with VCP
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SwissProt ID
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Synonyms
p37
Documentation
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