USP54 Antibody (YA8539)
(Synonyms: bA137L10.3; bA137L10.4; C10orf29)USP54 Antibody (YA8539) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to USP54.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
USP54 Antibody (YA8539) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to USP54.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Human recombinant protein fragment corresponding to amino acids 358-700 of human USP54 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
USP54 is a Deubiquitinase that specifically mediates 'Lys-63'-linked deubiquitination of substrates with a polyubiquitin chain composed of at least 3 ubiquitins. Specifically recognizes ubiquitin chain in position S2 and catalyzes cleavage of polyubiquitin within 'Lys-63'-linked chains. Not able to deubiquitinate substrates with shorter ubiquitin chains. Mediates deubiquitination of PLK4, maintaining PLK4 stability by reducing its ubiquitination-mediated degradation[1][2].
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Expression
Tissue_Specificity: Weakly expressed in a few tissues -
Isoforms & Post-Translational Modification
Q70EL1 has 7 isomers: Q70EL1-1: 187388 Da (predicted); Q70EL1-4: 45703 Da (predicted); Q70EL1-6: 100476 Da (predicted); Q70EL1-7: 170581 Da (predicted); Q70EL1-8: 84938 Da (predicted); Q70EL1-9: 79771 Da (predicted); Q70EL1-10: 84366 Da (predicted).
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SwissProt ID
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Synonyms
bA137L10.3; bA137L10.4; C10orf29
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