USP54 Antibody (YA8539)

Cat. No.: HY-P88855: Data Sheet User Guide for Antibodies
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USP54 Antibody (YA8539) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to USP54.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

USP54 Antibody (YA8539) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to USP54.

Host

Mouse

Clonality

Monoclonal

Species Reactivity

Human

SwissProt ID

Q70EL1

Immunogen

Human recombinant protein fragment corresponding to amino acids 358-700 of human USP54 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Deubiquitinase that specifically mediates 'Lys-63'-linked deubiquitination of substrates with a polyubiquitin chain composed of at least 3 ubiquitins (PubMed:39587316). Specifically recognizes ubiquitin chain in position S2 and catalyzes cleavage of polyubiquitin within 'Lys-63'-linked chains (PubMed:39587316). Not able to deubiquitinate substrates with shorter ubiquitin chains (PubMed:39587316). Mediates deubiquitination of PLK4, maintaining PLK4 stability by reducing its ubiquitination-mediated degradation (PubMed:36590171)

Expression：
Tissue_Specificity: Weakly expressed in a few tissues

Isoforms & Post-Translational Modification：Q70EL1 has 7 isomers: Q70EL1-1: 187388 Da (predicted); Q70EL1-4: 45703 Da (predicted); Q70EL1-6: 100476 Da (predicted); Q70EL1-7: 170581 Da (predicted); Q70EL1-8: 84938 Da (predicted); Q70EL1-9: 79771 Da (predicted); Q70EL1-10: 84366 Da (predicted).

Synonyms

bA137L10.3; bA137L10.4; C10orf29

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/nci-h1975-cell.html [Content Brief]