VAMP1 Antibody (YA2056)

Cat. No.: HY-P82311: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

VAMP1 Antibody (YA2056) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VAMP1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈	재고	수량
20 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

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VAMP1 Antibody (YA2056) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

VAMP1 Antibody (YA2056) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VAMP1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 13 kDa;

Observed band size: 16 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P23763

Gene ID

6843 [NCBI]

Immunogen

A synthesized peptide derived from human VAMP1 aa1-45/118.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Involved in the targeting and/or fusion of transport vesicles to their target membrane

Subcellular Localization：Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein; Synapse, synaptosome; Cytoplasmic vesicle membrane; Single-pass type IV membrane protein; Synapse, synaptosome; Mitochondrion outer membrane; Single-pass type IV membrane protein

Expression：
Tissue_specificity:Nervous system, skeletal muscle and adipose tissue

Isoforms & Post-Translational Modification：P23763 has 3 isomers: P23763-1: 12902 Da (predicted); P23763-3: 12765 Da (predicted); P23763-2: 12658 Da (predicted).
(Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type B (BoNT/B, botB) which probably hydrolyzes the 78-Gln-|-Phe-79 bond and inhibits neurotransmitter release (PubMed:22289120);(Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type D (BoNT/D, botD) which probably hydrolyzes the 61-Arg-|-Leu-62 bond and inhibits neurotransmitter release (PubMed:22289120). BoNT/D has low catalytic activity on this protein due to its sequence (PubMed:22289120). Note that humans are not known to be infected by C.botulinum type D;(Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type F (BoNT/F, botF) which probably hydrolyzes the 60-Gln-|-Lys-61 bond and inhibits neurotransmitter release (PubMed:22289120);(Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type X (BoNT/X) which probably hydrolyzes the 68-Arg-|-Ala-69 bond and inhibits neurotransmitter release (PubMed:29540745). It remains unknown whether BoNT/X is ever produced, or what organisms it targets

Subunit：Interacts with VAPA and VAPB

Database

Entrez Gene: 6843 Human ; 22317 Mouse ; 25624 Rat

SwissProt: P23763 Human ; Q62442 Mouse ; Q63666 Rat

OMIM: 108600 Human

Research Field

Neuroscience

Synonyms

SYB1; Synaptobrevin 1; Vamp1

각종 서류

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

VAMP1 Antibody (YA2056) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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VAMP1 Antibody (YA2056)

VAMP1 Antibody (YA2056) Featured Recommendations:

Product Detail

Background

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VAMP1 Antibody (YA2056) Related Classifications

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SAFETY DATA SHEET (SDS)

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