VIRMA Antibody (YA6837)
(Synonyms: DKFZp434I116 antibody; DKFZp781B2117 antibody; fSAP121 antibody; KIAA1429 antibody; MGC138493 antibody; MGC141940 antibody; MSTP054 antibody; Protein virilizer homolog antibody; VIR_HUMAN antibody; )VIRMA Antibody (YA6837) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VIRMA.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF, IHC-P, FC, IP
-
Reactivity :
Human, Rat, Monkey
-
Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
FC
FC: Flow Cytometry
|
IP
IP: Immunoprecipitation
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:2000 | 1:50-1:100 | 1:200-1:1000 | 1:1000 | 1-2μg/sample |
Product Details
VIRMA Antibody (YA6837) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VIRMA.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Rat, Monkey
-
Observed Molecular WeightObserved band size: 240 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 202 kDa
Recombinant protein within human VIRMA aa 1,431-1,730.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
VIRMA is an Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA)[1][2].
-
Subcellular Localization
Nucleus speckle,Nucleus, nucleoplasm,Cytoplasm
-
Isoforms & Post-Translational Modification
Q69YN4 has four isomers: Q69YN4-1: 202025 Da (predicted); Q69YN4-2: 154472 Da (predicted); Q69YN4-3: 201057 Da (predicted); Q69YN4-4: 128734 Da (predicted).
-
Subunit
Component of the WMM complex, a N6-methyltransferase complex composed of a catalytic subcomplex, named MAC, and of an associated subcomplex, named MACOM (PubMed:29507755)
-
SwissProt ID
-
Synonyms
DKFZp434I116 antibody; DKFZp781B2117 antibody; fSAP121 antibody; KIAA1429 antibody; MGC138493 antibody; MGC141940 antibody; MSTP054 antibody; Protein virilizer homolog antibody; VIR_HUMAN antibody;
Documentation
Powered by Bioz
