VIRMA Antibody (YA6837)

Cat. No.: HY-P87144: Data Sheet User Guide for Antibodies
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VIRMA Antibody (YA6837) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VIRMA.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

VIRMA Antibody (YA6837) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VIRMA.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 202 kDa;

Observed band size: 240 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat, Monkey

SwissProt ID

Q69YN4

Gene ID

25962 [NCBI]

Immunogen

Recombinant protein within human VIRMA aa 1,431-1,730.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:100
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:1000
IP IP: Immunoprecipitation	1-2μg/sample

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:24981863, PubMed:29507755). Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites (PubMed:29507755). Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA) (PubMed:29507755)

Subcellular Localization：Nucleus speckle,Nucleus, nucleoplasm,Cytoplasm

Isoforms & Post-Translational Modification：Q69YN4 has four isomers: Q69YN4-1: 202025 Da (predicted); Q69YN4-2: 154472 Da (predicted); Q69YN4-3: 201057 Da (predicted); Q69YN4-4: 128734 Da (predicted).

Subunit：Component of the WMM complex, a N6-methyltransferase complex composed of a catalytic subcomplex, named MAC, and of an associated subcomplex, named MACOM (PubMed:29507755)

Synonyms

DKFZp434I116 antibody; DKFZp781B2117 antibody; fSAP121 antibody; KIAA1429 antibody; MGC138493 antibody; MGC141940 antibody; MSTP054 antibody; Protein virilizer homolog antibody; VIR_HUMAN antibody;

Documentation

User Guide for Antibodies (1077 KB)