VIRMA - vir like m6A methyltransferase associated Gene

Also Known as MSTP054; fSAP121; KIAA1429

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25962

About VIRMA

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:94,487,689-94,553,469 (from NCBI)

This gene has 9 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in testis (RPKM 11.6), ovary (RPKM 8.4) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in mRNA alternative polyadenylation and mRNA methylation. Located in cytosol and nuclear speck. Colocalizes with RNA N6-methyladenosine methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

VIRMA Products (2)

mRNA Protein Name
NM_015496.5 NP_056311.2 protein virilizer homolog isoform 1
NM_183009.3 NP_892121.1 protein virilizer homolog isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15161933 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA processing IDA
IDA: Inferred from direct assay
29507755 GOA
involved in mRNA processing IMP
IMP: Inferred from mutant phenotype
24981863 GOA
Cellular Component GO Annotation Evidence References Source
part of RNA N6-methyladenosine methyltransferase complex IDA
IDA: Inferred from direct assay
24981863 GOA
part of RNA N6-methyladenosine methyltransferase complex IPI
IPI: Inferred from physical interaction
29507755 GOA
located in nuclear speck IDA
IDA: Inferred from direct assay
24100041 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
24100041 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein virilizer homolog

  • functional spliceosome-associated protein 121

VIRMA Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
VIRMA Q69YN4 YWHAZ Homo sapiens P63104
Pull Down
15161933
Intra
VIRMA Q69YN4 PRPF6 Homo sapiens O94906
Anti Bait CoIP
35709258
Cross: Cross-species interaction Intra: Intraspecies interaction

VIRMA Antibodies

Cat. No. Product Name Application Reactivity
HY-P87144 VIRMA Antibody (YA6837) WB, ICC/IF, IHC-P, FC, IP Human, Rat, Monkey

Related Diseases

Diseases Alias
Wilms Tumor 1

  • Nephroblastoma

  • Wilms Tumor

  • WT1

  • Wilms' Tumor

  • Bilateral Wilms Tumor

  • Wilms Tumor, Type 1

  • Wilms Tumor, Somatic

  • Adult Nephroblastoma

  • Wt1 Disorder

  • Renal Embryonic Tumor

  • Adult Kidney Wilms Tumor

  • Childhood Kidney Wilms Tumor

  • Nonanaplastic Kidney Wilms Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15657 VIRMA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21081 Virma Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27598 Virma Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus VIRMA MGD MGI:1913435
Macaca mulatta VIRMA VGNC VGNC:79436
Canis familiaris VIRMA VGNC VGNC:48267
Bos taurus VIRMA VGNC VGNC:36801
Felis catus VIRMA VGNC VGNC:66947
Rattus norvegicus VIRMA RGD RGD:1559904
Others VIRMA NCBI