country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N20718

Copy Link Print Information

Agastinol

Agastinol is a naturally sourced caspase-3 inhibitor. Agastinol inhibits the expression of caspase-3 and apoptosis induced by Etoposide (HY-13629) in human leukemia U937 cells. Agastinol can be used in leukemia-related research.

For research use only. We do not sell to patients.

CAS No.: 413615-33-5
Formula: C₂₇H₂₈O₈
Molecular Weight:480.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Agastinol Chemical Structure

CAS No.: 413615-33-5

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Caspase 3

15.2 μg/mL (IC₅₀)

All Caspase Isoforms :

In Vitro

Agastinol (compound 1) inhibits the expression of caspase-3 in human leukemia U937 cells induced by Etoposide (HY-13629), with an IC₅₀ of 15.2 μg/mL^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 413615-33-5
Molecular Weight 480.51
Formula C₂₇H₂₈O₈
SMILES

C(OC(=O)C1=CC=C(O)C=C1)[C@H]2[C@@H](OC[C@H]2CC3=CC(OC)=C(O)C=C3)C4=CC(OC)=C(O)C=C4
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zielińska S, et al. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochemistry Reviews, 2014, 13: 391-416.

[2]. Lee C, et al. Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay. Journal of natural products. 2002 Mar;65(3):414-6. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Agastinol

All Caspase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Agastinol Related Classifications

HY-N20718 Related Classifications