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Cat. No.: HY-109110R

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Avasopasem manganese (Standard)

(Synonyms: GC-4419 (Standard); M-40419 (Standard))

Avasopasem manganese (Standard) is the analytical standard of Avasopasem manganese (HY-109110). This product is intended for research and analytical applications. Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer.

For research use only. We do not sell to patients.

CAS No.: 435327-40-5
Formula: C₂₁H₃₅Cl₂MnN₅
Molecular Weight:483.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Avasopasem manganese (Standard) Chemical Structure

CAS No.: 435327-40-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 435327-40-5
Molecular Weight 483.38
Formula C₂₁H₃₅Cl₂MnN₅
SMILES

[Cl-][Mn+2]1234([N]5=C6C[NH]1[C@](CCCC7)([H])[C@@]7([H])[NH]2CC[NH]3[C@]8([H])[C@@](CCCC8)([H])[NH]4CC5=CC=C6)[Cl-]
Synonyms

GC-4419 (Standard); M-40419 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Anderson CM, et al. Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer [published correction appears in J Clin Oncol. 2020 Jan 20;38(3):288]. J Clin Oncol. 2019;37(34):3256-3265. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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