Azaspirene
Azaspirene ((-)-Azaspirene) is an angiogenesis and Raf-1 activation inhibitor isolated from the fungus Neosartorya sp. Azaspirene inhibits vascular endothelial growth factor (VEGF)-induced human umbilical vein endothelial cell (HUVEC) migration and Raf-1 activation, but has no effect on the activation of kinase insert domain-containing receptor/fetal liver kinase 1 (VEGF receptor 2).
For research use only. We do not sell to patients.
- CAS No.: 461644-34-8
- Formula: C21H23NO5
- Molecular Weight:369.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 461644-34-8
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Molecular Weight 369.41
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Formula C21H23NO5
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SMILES
O[C@@H]1[C@]2(C(N[C@@]1(O)CC3=CC=CC=C3)=O)OC(/C=C/C=C/CC)=C(C2=O)C
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Synonyms
(-)-Azaspirene
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Structure Classification
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Initial Source
Neosartorya sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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