ADP-ribosylhydrolase ARH1

Definition:

Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.

References:

[1]. T Takada, et al. Cloning and site-directed mutagenesis of human ADP-ribosylarginine hydrolase. J Biol Chem. 1993 Aug 25;268(24):17837-43. [Content Brief]

[2]. Johannes Gregor Matthias Rack, et al. (ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition. Cell Chem Biol. 2018 Dec 20;25(12):1533-1546.e12. [Content Brief]

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