All-trans retinoic acid-induced differentiation factor

Definition:

Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway.

References:

[1]. Xuan Zou, et al. NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation. FEBS Lett. 2011 Aug 4;585(15):2410-8. [Content Brief]

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