1. Biology Dictionary
  2. Ankyrin repeat domain-containing protein 13D

Ankyrin repeat domain-containing protein 13D

Definition:

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

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