Centrosome-associated protein 350

Definition:

Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation.

References:

[1]. Mikael Le Clech, et al. Role of CAP350 in centriolar tubule stability and centriole assembly. PLoS One. 2008;3(12):e3855. [Content Brief]

[2]. Bahareh A Mojarad, et al. CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme. Open Biol. 2017 Jun;7(6):170114. [Content Brief]

[3]. Xiumin Yan, et al. A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Mol Biol Cell. 2006 Feb;17(2):634-44. [Content Brief]

[4]. Aurélie Hoppeler-Lebel, et al. Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. J Cell Sci. 2007 Sep 15;120(Pt 18):3299-308. [Content Brief]

[5]. Hansa Patel, et al. Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor alpha are altered by the centrosome-associated protein CAP350. J Cell Sci. 2005 Jan 1;118(Pt 1):175-86. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.