Cytochrome P450 11B2, mitochondrial
Definition:
References:
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[1]. Natallia Strushkevich, et al. Structural insights into aldosterone synthase substrate specificity and targeted inhibition. Mol Endocrinol. 2013 Feb;27(2):315-24. [Content Brief]
[2]. Stephanie Bechtel, et al. The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme. Eur J Biochem. 2002 Feb;269(4):1118-27. [Content Brief]
[3]. L Pascoe, et al. Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):4996-5000. [Content Brief]
[4]. S Portrat-Doyen, et al. Isolated aldosterone synthase deficiency caused by simultaneous E198D and V386A mutations in the CYP11B2 gene. J Clin Endocrinol Metab. 1998 Nov;83(11):4156-61. [Content Brief]
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